Matching
BCR stimulation and TCR stimulation generally activate similar downstream signaling modules, but do so using related, but not identical, signaling proteins. From the list below, match each B cell protein to its T cell counterpart.
Premises:
Syk
BTK
Ig-α or Ig-β
SLP-65
Lyn, Blk or Fyn
CD19/CD21/CD81
Responses:
CD3ζ
PLC-Υ
PI-3-kinase
LAT
ITK
SLP-76
CD28
Vav
ZAP-70
Lck
Correct Answer:
Premises:
Responses:
CD3ζ
PLC-Υ
PI-3-kinase
LAT
ITK
SLP-76
CD28
Vav
ZAP-70
Lck
Premises:
CD3ζ
PLC-Υ
PI-3-kinase
LAT
ITK
SLP-76
CD28
Vav
ZAP-70
Lck
Responses:
Related Questions
Q32: Diacyl-glycerol (DAG) is one of the
Q33: Antigen receptor signaling pathways are initiated
Q34: Following TCR stimulation, the small GTPase Ras
Q35: A new strain of immunodeficient mice
Q36: Wiskott-Aldrich syndrome is an immunodeficiency disease due
Q37: The B cell co-receptor, composed of
Q39: A mutant B cell line is
Q40: Many receptors of the immune system activate
Q41: Following TCR or BCR signaling, the most
Q42: 'Checkpoint blockade' is a therapeutic strategy based