The Conversion of Glucose-6-Phosphate to Glucose-1-Phosphate Has a ΔG´° of

The conversion of glucose-6-phosphate to glucose-1-phosphate has a ΔG´° of + 8.4 kJ/mol. How can a reaction such as this proceed in a cell?

A) it must be coupled to ATP hydrolysis
B) the product must be rapidly used in a subsequent step of the pathway
C) it can only occur with the help of an enzyme
D) this reaction can not proceed and must go in the reverse manner
E) both B and C are correct

Correct Answer:

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