An Important Difference Between a Class I and Class II

An important difference between a class I and class II aminoacyl-tRNA synthetase is:

A) The two classes proceed through different aminoacyl-AMP intermediates.
B) Class I synthetases first attach the amino acid to the 2'-hydroxyl on ribose, whereas class II attach them to the 3'-hydroxyl.
C) Class I synthetases attach amino acids to the 5'-end of the tRNA, whereas class II attach them to the 3'-end.
D) The 5'-end of the tRNA molecule is phosphorylated only for those tRNAs recognized by class I synthetases.
E) None are true.

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