Untreated HIV Infection Will Lead to a Decrease in CD4-Expressing

Untreated HIV infection will lead to a decrease in CD4-expressing T cells. Which part of the immune response is affected by this lowering of CD4-expressing T cell concentration?

A) The ability of B cells to produce memory B cells
B) The ability of macrophages to recognize specific antigenic determinants
C) The ability of cytotoxic T cells to kill target cells
D) Both a and b
E) Both a and c

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