Which Are Indications for Discontinuing Growth Hormone (GH)therapy in Children

Which are indications for discontinuing growth hormone (GH) therapy in children with documented growth hormone deficiency? (Select all that apply.)

A) Epiphyseal closure has begun.
B) A satisfactory adult height has been achieved.
C) Serum GH levels have been normal for 12 consecutive months.
D) Normal serum growth hormone levels occur.
E) The child no longer responds to the hormone.

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