Essay
Two groups of rats have a small pellet implanted under the skin.In Group A rats the pellet contains morphine, which is slowly absorbed over a 72 hour period.In Group B rats the pellet contains an inert substance.The rats are kept in their home cages for the three days after the pellet implantation.Both groups are then tested for analgesia by being injected intraperitoneally with a small dose of morphine.This test consists of the rats being placed on a hot surface and they are timed to see how long it takes them to lick their paws.(It is assumed that the longer it takes the rats to lick their paws, the more the analgesia.) Group A rats display much less of an analgesic response than Group B rats.Is this tolerance phenomenon more compatible with a pharmacodynamic or a context specific mechanism for tolerance development? Explain your reasoning.
Correct Answer:
Verified
A never practiced the paw-licking behavi...View Answer
Unlock this answer now
Get Access to more Verified Answers free of charge
Correct Answer:
Verified
View Answer
Unlock this answer now
Get Access to more Verified Answers free of charge
Q1: A researcher is investigating some of the
Q2: Depending upon how frequently they are activated,
Q3: If two drugs exert the same pharmacodynamic
Q5: What is a pharmacological reason for receptor
Q6: With the exception of nicotine, the first
Q7: Which type of tolerance is most directly
Q8: Which of the following defense mechanisms prevents
Q9: Which type of context-specific process that results
Q10: Secondary psychological dependence is most likely to
Q11: The hypothesis that drug tolerance is due