Compound "K" Is the Ultimate Product of a Linear Metabolic $\to$

Compound "K" is the ultimate product of a linear metabolic pathway consisting of ten enzymatically catalyzed reactions as shown below.
1 2 3 4 5 6 7 8 9 10
A $\to$ B $\to$ C $\to$ D $\to$ E $\to$ F $\to$ G $\to$ H $\to$ I $\to$ J $\to$ K
Complete the following description.
If "K" inhibits activity of enzyme "5",then enzyme "5" is under ___ control.If enzyme "3" becomes activated in response to activity of protein kinase A only when compound "A" is present,then enzyme "3" is under ___ control.If enzyme "2" is only expressed in the presence of high concentrations of "A," then enzyme "2" is under ___ control.If all of these are true,high concentrations of "__" will decrease the flux through the pathway.

A) covalent modification;allosteric;genetic;A
B) allosteric;covalent modification;genetic;K
C) genetic;allosteric;genetic;K
D) allosteric;genetic;genetic;K
E) allosteric;genetic;genetic;A

Correct Answer:

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