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A 45-Year-Old Patient Shows Marked Cognitive Impairment That Has Developed

Question 15

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A 45-year-old patient shows marked cognitive impairment that has developed progressively over several months.A family member reports the patient's father had early-onset dementia.What research-based information can be given to the family in response to their concerns about the patient developing early-onset dementia?


A) The risk for developing the condition is about 50% only if both parents were affected.
B) The greatest risk exists for relatives of individuals diagnosed with Alzheimer disease before age 55 years.
C) Added risk is present only for people with Down syndrome, so relatives without Down syndrome are essentially safe.
D) Results of the research on genetic predisposition and its effect on the development of early-onset dementia are still unclear.

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