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Drug CandidateIC50(nmol)Log (P)Cmax (µM)BioavailabilityA0

Question 3

Multiple Choice

Drug candidateIC50(nmol) Log (P) Cmax (µM) BioavailabilityA0.44.67<0.1B0.013.70<0.1C0.33.690.7D0.62.9211Consider the information concerning a related class of potential drugs in the table above.Which one is least soluble in water and most hydrophobic?


A) A
B) B
C) C
D) D
E) They are all equally soluble in water.

Correct Answer:

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