How Does a Primary Adenoma Cause Thyroid and Adrenal Hypofunction

How does a primary adenoma cause thyroid and adrenal hypofunction?

A) The tumor metastasizes to the thyroid and adrenal glands through the lymphatic system causing reduce secretion of necessary hormones.
B) The tumor has a paradoxical effect on adjacent cells,which results in hyposecretion of other anterior pituitary hormones.
C) The tumor invades the hypothalamus adjacent to it and causes a reduction in the amount of hormones produced.
D) The tumor releases tumor markers that occupy the hormone receptor sites of other endocrine organs.

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