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Irradiation Prevents Mice from Generating Their Own T Cells

Question 31

Multiple Choice

Irradiation prevents mice from generating their own T cells.When the immune systems of irradiated mice are reconstituted with unfractionated CD4 cells,the recipients show no signs of autoimmune disease.However,if the T cells are depleted of the CD4+CD25+ subset prior to transfer,recipients show multi-organ autoimmunity.This result demonstrates the role of _____ in suppressing autoimmunity.


A) cytotoxic T cells
B) helper T cells
C) regulatory T cells
D) all of the above

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