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Electrospray Ionization Is One of Many Techniques Interfacing Chromatography with Mass

Question 17

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Electrospray ionization is one of many techniques interfacing chromatography with mass spectroscopy.Which is NOT true for electrospray ionization?


A) The steel nebulizer is held at 0 V while the spray chamber is held at −3500 V.
B) The strong electric field between the nebulizer and spray chamber creates a fine aerosol.
C) The glass capillary leading to the mass spectrometer is held at a potential of −4500 V to attract the gas phase cations.
D) Typically the ions that vaporize from aerosol droplets were already charged while on the chromatography column.
E) There is minimal fragmentation,but fragmentation can be increased by collisionally activated dissociation.

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