Based on Our Modern Understanding,what Revisions Are Necessary to the Original

Based on our modern understanding,what revisions are necessary to the original one-gene / one-enzyme hypothesis?

A) Alternative splicing allows one gene to encode multiple polypeptides.
B) Some genes encode RNAs, not enzymes.
C) Some genes encode lipids, not enzymes.
D) Some genes encode polypeptides that are not enzymes, such as structural proteins.
E) Proteins as functional units may be composed of several polypeptides, so genes may encode just one polypeptide within a larger protein.

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