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A 60-Year-Old Patient Visits His General Practitioner Because of Fatigue

Question 10

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A 60-year-old patient visits his general practitioner because of fatigue and unexplained bruising.Physical examination revealed a frail, thin, pale man with widespread bruising.A CBC is ordered, and comes back abnormal.Peripheral blood smear examination revealed abnormal granularity of platelets and leukocytes.Red cells appear dimorphic.Bone marrow analysis is performed, and there were 20% ringed sideroblasts with dysplastic changes in RBC and WBC precursors.No cytogenetic abnormalities were detected.Based on this information, what is a probable diagnosis?


A) Acute leukemia
B) Chronic lymphocytic leukemia
C) Myelodysplastic syndrome
D) Myeloproliferative syndrome

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