Which of the Following Statements Is True Regarding Hemoglobinopathies but False

Which of the following statements is true regarding hemoglobinopathies but false in thalassemia?

A) Abnormal hemoglobin will polymerize inside erythrocytes, altering red cell shape.
B) Novel hemoglobins composed of abnormal combinations of normal globin chains can be detected on hemoglobin electrophoresis.
C) Elevations in embryonic and fetal hemoglobins can be observed.
D) The amino acid sequence of the globin chains of the abnormal hemoglobins is normal.

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