What Feature Distinguishes CML from a Leukemoid Reaction

What feature distinguishes CML from a leukemoid reaction?

A) CML has no blasts in the peripheral blood; in a leukemoid reaction, blasts are common.
B) CML often has abnormal platelet morphology, and leukemoid reaction has normal platelets.
C) LAP is increased in CML and decreased in leukemoid reaction.
D) Chromosome karyotype is abnormal in leukemoid reaction and normal in CML.

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