What Is the Reason That Concentrations of Topical Anesthetic Agents

What is the reason that concentrations of topical anesthetic agents are higher than those of their injectable counterparts?

A) Topical agents are not natural vasoconstrictors like injectable anesthetic agents.
B) They facilitate high plasma concentrations of topical anesthetic agents.
C) They facilitate diffusion of the topical anesthetic agent through the mucous membranes.
D) With topical anesthetic agents,systemic absorption decreases.

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