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The Number of MHC Protein Combinations Possible in a Given

Question 84

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The number of MHC protein combinations possible in a given population is enormous. However, an individual in that population has only a couple of MHC possibilities. Why?


A) The MHC proteins are made from several different gene regions that are capable of rearranging in a number of ways.
B) MHC proteins from one individual can only be of class I or class II.
C) Each of the MHC genes has a large number of alleles, but each individual only inherits 2 for each gene.
D) Once a B cell has matured in the bone marrow, it is limited to two MHC response categories.
E) Once a T cell has matured in the thymus, it can only respond to two MHC categories.

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