A Patient Who Uses Every-Other-Day Prednisone Therapy for Rheumatoid Arthritis

A patient who uses every-other-day prednisone therapy for rheumatoid arthritis complains of not feeling as well on the non-prednisone days and asks the nurse about taking prednisone daily instead. The best response to the patient is that

A) an every-other-day schedule mimics the normal pattern of cortisol secretion from the adrenal gland.
B) glucocorticoids are taken on a daily basis only when they are being used for replacement therapy.
C) if it improves the symptoms, it would be acceptable to take half the usual dose every day.
D) there is less effect on normal adrenal function when prednisone is taken every other day.

Correct Answer:

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