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Why Has Dihydrofolate Reductase Been Identified as a Potential Target

Question 90

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Why has dihydrofolate reductase been identified as a potential target for chemotherapy in the treatment of cancer?


A) It is a hormone that is a primary control agent of the rate of mitosis.
B) It is a DNA binding protein that activates a cancer oncogene.
C) It is essential in DNA synthesis.Cell division will not occur without it.
D) It selectively binds to a receptor on the surface of cancer cells and inactivates them.

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