How Is Progression Different from Metastasis

How is progression different from metastasis?

A) Progression cannot occur unless the process of metastasis occurs first.
B) Metastasis occurs in both benign and malignant cells, whereas progression is a feature that is unique to malignant cells.
C) Metastasis is dependent on gene mutations in suppressor genes, and progression is dependent on gene mutations in oncogenes.
D) Progression involves continual gene changes in a cancer cell that enhance its degree of malignancy, whereas metastasis is the ability of the cell to invade other tissues.

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