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How Does Intravenous Enzyme-Replacement Therapy for Gaucher Disease Reduce the Organ

Question 23

Multiple Choice

How does intravenous enzyme-replacement therapy for Gaucher disease reduce the organ storage of glucosylceramide?


A) The enzyme increases the destruction of glucosamine-filled macrophages.
B) The drug acts as a cofactor, increasing the activity of the mutated enzyme.
C) The drug increases production of all blood cells in the bone marrow, including white blood cells, which have not stored glucosylceramide.
D) The enzyme is absorbed through the plasma membranes of affected cells and converts the stored glucosylceramide into its constituent molecules.

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