During Cell Division a Piece of a Chromosome Breaks Off

During cell division a piece of a chromosome breaks off and reattaches to the same chromosome,but the piece is now in reverse order.How would this abnormality affect the chromosome?

A) An extra copy of the chromosome will be made to ensure normal function.
B) The inverted section will be deleted to prevent problems.
C) The chromosome will take on a circular configuration.
D) Genes in the section that was inverted could lose normal function.

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