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Welsh and Colleagues (1995) Removed Neurons from the Suprachiasmatic Nuclei

Question 22

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Welsh and colleagues (1995) removed neurons from the suprachiasmatic nuclei (SCN) of a newborn rat and grew them in a tissue culture. They then added tetrodotoxin, a chemical that prevents action potentials that require sodium ions. When the tetrodotoxin was washed out of the cells,


A) the firing rhythm reappeared, but the phase was disrupted by the 2.5 day application of tetrodotoxin.
B) the firing rhythm reappeared, with a phase predicted by the initial cycles.
C) the neurons failed to resume their original spontaneous rhythm in the rate of their firing.
D) the researchers found that the cells had died.

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