What Is the Factor in the Evolution of Neuronal Membranes

What is the factor in the evolution of neuronal membranes that limits the physical distance over which electrical information integration can occur?

A) Cranio-electroconductivity
B) The hormonal output of neurons.
C) The energy level of the neuronal electrochemical gradient
D) The electrical properties of neuronal membranes
E) The distance of environmental input signalling from external receptors

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