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-Refer to Exhibit 3A

Question 18

Multiple Choice

 Exhibit 3A (for this chapter)   Amino acid α-carboxyl group pK a α-amino group pK a  R-group pK  Ala 2.39.7 Arg 2.29.012.5 Asn or Gln 2.19.04.0 Asp or Glu 2.29.88.3 Cys 1.710.86.0 His 1.89.2 Ser 2.29.210.1\begin{array}{l}\text { Exhibit } \mathbf { 3 A } \text { (for this chapter) }\\\begin{array} { l l l l } \text { Amino acid } & \boldsymbol { \alpha } \text {-carboxyl group pK a } & \boldsymbol { \alpha } \text {-amino group pK a } & \text { R-group pK } \\\hline \text { Ala } & 2.3 & 9.7 & \\\text { Arg } & 2.2 & 9.0 & 12.5 \\\text { Asn or Gln } & 2.1 & 9.0 & 4.0 \\\text { Asp or Glu } & 2.2 & 9.8 & 8.3 \\\text { Cys } & 1.7 & 10.8 & 6.0 \\\text { His } & 1.8 & 9.2 & \\\text { Ser } & 2.2 & 9.2 & 10.1\end{array}\end{array}
-Refer to Exhibit 3A. The pI of an amino acid is the pH at which it has a zero net charge. What is the increasing order of isoelectric points (low pH to high) for these three amino acids?


A) ALA, HIS, ASP
B) ASP, ALA, HIS
C) HIS, ALA, ASP
D) ALA, ASL, HIS
E) ASP, HIS, ALA

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