Cytarabine Is a Nucleoside Analog Often Used as a Chemotherapeutic

Cytarabine is a nucleoside analog often used as a chemotherapeutic agent. Which of the following is true of chemically induced arachnoiditis on intrathecal injection?

A) Chemically induced arachnoiditis does not occur with cytarabine use.
B) Dexamethasone should be co-administered to reduce arachnoiditis.
C) Chemically induced arachnoiditis only occurs if the cytarabine is given too slowly. Otherwise, it is not a problem.
D) An OTC analgesic should be co-administered with the cytarabine to limit chemically induced arachnoiditis.

Correct Answer:

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