The Enteric Nervous System Plays the Most Important Role in Mediating

The enteric nervous system plays the most important role in mediating serotonergic effects on gut function. However, researchers originally thought that enterochromaffin cells played the most important role because

A) experiments with knockout mice suggested greater involvement of enterochromaffin cells.
B) of the sheer number of enterochromaffin cells in the gut.
C) of the high density of 5-HT in enterochromaffin cells.
D) enterochromaffin 5-HT is released directly into the bloodstream.

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