Which Statement Concerning the Receptor Subtypes Involved in Psychostimulant Effects

Which statement concerning the receptor subtypes involved in psychostimulant effects is true?

A) The locomotor-stimulating effects of cocaine involve the D₅ receptor.
B) D₂ receptors are required for cocaine self-administration.
C) Pimozide, a D₂ receptor blocker, completely eliminates amphetamine-induced euphoria.
D) D₁ receptor knockout mice are insensitive to both the locomotor stimulating and reinforcing effects of cocaine.

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