Which Statement Supports the Hypothesis That GHB Acts on the GABA_B

Which statement supports the hypothesis that GHB acts on the GABA_B receptor?

A) GHB has definitively been shown to be metabolized in the brain to GABA, which then stimulates GABA_B receptors.
B) GHB has been shown to have a high affinity for the GABA_B receptor.
C) The behavioral and physiological effects of GHB can be reversed by baclofen.
D) Mice genetically engineered to lack the GABA_B receptor do not show behavioral or physiological responses to GHB.

Correct Answer:

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