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β\beta -Arrestin Binds to Phosphorylated G Protein-Coupled Receptors, Binding Raf, MEK

Question 100

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β\beta -arrestin binds to phosphorylated G protein-coupled receptors, binding Raf, MEK, and ERK into the complex and linking the G protein-coupled signal pathway to the ERK signal pathway. This is an example of inhibitory crosstalk.

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