Multiple Choice
The PDGF receptor is a proto-oncogene (a normal cellular gene that becomes oncogenic when mutated) . Which statement about the PDGF receptor is true?
A) The oncogenic mutation occurs at the intracellular amino terminal end of the receptors.
B) The oncogenic mutation constitutively represses the intracellular kinase activity of the protein.
C) The oncogenic mutation generates a receptor that is no longer dependent on ligand for activation.
D) The PDGF protein monomer activates cell proliferation via tyrosine kinase activity.
Correct Answer:
Verified
Correct Answer:
Verified
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