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A 15-Year-Old Boy Developed Generalized Lymphadenopathy, Accompanied by Fever and Malaise

Question 15

Multiple Choice

A 15-year-old boy developed generalized lymphadenopathy, accompanied by fever and malaise. A lymph node biopsy specimen showed that the architecture of the lymph nodes was erased and the nodes were infiltrated with moderately large lymphoid cells. There were numerous mitoses and apoptotic bodies. Between the B lymphocytes, there were phagocytic macrophages, imparting a "starry-sky" appearance to the lymph node. Which of the following is the most likely diagnosis?


A) Follicular lymphoma
B) Large B-cell lymphoma
C) Chronic lymphocytic leukemia/small lymphocytic lymphoma
D) Burkitt lymphoma
E) Multiple myeloma

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