Centrally-Acting Antispasm Drugs Such as Cyclobenzaprine (Flexeril)and Carisoprodol (Soma)were Originally

Centrally-acting antispasm drugs such as cyclobenzaprine (Flexeril) and carisoprodol (Soma) were originally thought to inhibit polysynaptic reflexes in the spinal cord (polysynaptic inhibitors) but these drugs most likely work by producing

A) decreased acetylcholine release at the neuromuscular junction
B) decreased calcium release from the sarcoplasmic reticulum
C) generalized sedation in the CNS
D) inhibition of myosin ATPase activity
E) increased vasodilation of skeletal muscle vasculature

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