What Is an Example of Cross-Sensitization in the Context of Drug

What is an example of cross-sensitization in the context of drug and sugar addiction?

A) Developing a tolerance to sugar preference and amphetamine hyperactivity.
B) Following a week of amphetamine injections, rats find sugar aversive.
C) A hyperactivity to a low dose of a drug of abuse following eating sugar for a week.
D) Showing a decreased preference for sugar following a week of drug restriction.

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