After Receiving a Sulfonamide Compound for a Urinary Tract Infection

After receiving a sulfonamide compound for a urinary tract infection, a woman develops a life-threatening immune vasculitis known as the Stevens-Johnson syndrome.
Which mechanism is usually responsible for this condition?

A) IgE-mediated release of histamine from mast cells and basophils
B) formation of sensitized lymphocytes
C) complement-mediated cell lysis
D) delayed hypersensitivity reactions
E) deposition of immune complexes in blood vessel walls

Correct Answer:

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