A Researcher Is Working to Develop a New Medication Fot

A researcher is working to develop a new medication fot treatment fo patient with heart failure. if this treatment improve patient symptoms by increasing urine output and decreasing peripheral vascular resistance.  The medication works by inhibiting a metalloprotease to prolong the action of endogenous polypeptides.  These polypeptides are most likely secreted by which of the following cell types?

A) Adrenal zona glomerulosa cells
B) Cardiomyocytes
C) Hepatic stellate cells
D) Myocardial Purkinje fibers
E) Renal juxtaglomerular cells
F) Vascular endothelial cells

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