A Research Hospital's Nephrologists Are Looking into the Physiologic Changes

A research hospital's nephrologists are looking into the physiologic changes that occur in diabetes insipidus. The group creates a technique that allows tubular urine sampling in experimental animals with human-like physiology. Following hypophysectomy, tubular fluid samples are collected from multiple sites throughout the nephron. Fluid from which of the following sampling sites is most likely to have the highest osmolarity in the absence of antidiuretic hormone?

A) A
B) B
C) C
D) D
E) E
F) F

Correct Answer:

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