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A 4-Year-Old Boy with Acute Lymphoblastic Leukemia Is Admitted to the Hospital

Question 173

Multiple Choice

A 4-year-old boy with acute lymphoblastic leukemia is admitted to the hospital to undergo allogeneic bone marrow transplantation. Two weeks after the conditioning regimen is started, he develops a temperature of 38.5°C (101.3°F) . Laboratory studies show:
Hemoglobin 8 g/dL
Leukocyte count 1400/mm3
Segmented neutrophils 15%
Eosinophils 0.5%
Lymphocytes 84%
Monocytes 1%
Platelet count 110,000/mm3
Which of the following is the most appropriate pharmacotherapy for this patient?


A) Alkylating chemotherapeutic agent
B) Transforming growth factor-Beta
C) Erythropoietin
D) Interleukin-5
E) Granulocyte-macrophage colony-stimulating factor
F) Thrombopoietin
G) Interleukin-2

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