A 68-Year-Old Woman Comes to the Office Due to Increasing

A 68-year-old woman comes to the office due to increasing low back pain.  The pain is constant and worsens at night.  She has also had a 6.8-kg (15-lb) weight loss over the past 3 months.  Medical history is significant for osteoporosis and hypothyroidism.  Family history is significant for breast cancer in her mother.  She has smoked 1 pack of cigarettes daily for 30 years and drinks 1 or 2 glasses of wine every day.  Further evaluation of the patient reveals microscopic hematuria.  Laboratory results are as follows: Which of the following is the most likely cause of this patient's hematologic findings?

A) Arteriovenous malformation
B) Excess erythropoietin production
C) Extramedullary hematopoiesis
D) Myeloproliferative disorder
E) Reduced plasma volume

Correct Answer:

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