A 16-Year-Old Boy Comes to the Physician Because His Parents

A 16-year-old boy comes to the physician because his parents are concerned about gynecomastia. Physical examination shows bilateral gynecomastia, sparse pubic hair. Genital examination shows microphallus and bilateral swelling in the groin region.. Serum studies show increased levels of luteinizing hormone and normal follicle-stimulating hormone and an increased serum testosterone. Semen analysis reveals severe oligospermia.  Which of the following mechanisms is the most likely cause of this patient's condition?

A) Androgen receptor dysfunction
B) Damage to seminiferous tubules
C) Ejaculatory duct obstruction
D) Exogenous androgen use
E) Impaired Leydig cell function

Correct Answer:

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