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A 35-Year-Old Guy Who First Observed Nontender Cervical Lymphadenopathy While

Question 154

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A 35-year-old guy who first observed nontender cervical lymphadenopathy while shaving is currently undergoing evaluation. Following a biopsy, the histology of the lymph nodes may be seen in the low-magnification picture below. A 35-year-old guy who first observed nontender cervical lymphadenopathy while shaving is currently undergoing evaluation. Following a biopsy, the histology of the lymph nodes may be seen in the low-magnification picture below.   Which of the following patterns would be most likely to be seen using cytogenetic analysis? A) BCL-2 overexpression B) BCR-ABL rearrangement C) C-MYC overexpression D) Constitutive tyrosine kinase activation E) N-MYC overexpression Which of the following patterns would be most likely to be seen using cytogenetic analysis?


A) BCL-2 overexpression
B) BCR-ABL rearrangement
C) C-MYC overexpression
D) Constitutive tyrosine kinase activation
E) N-MYC overexpression

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