A 77-Year-Old Man Is Sent to the Emergency Room Because

A 77-year-old man is sent to the emergency room because of syncope, shortness of breath, and severe chest discomfort. When it comes to coronary artery disease, which was treated with right coronary artery stenting five years ago, medical history is important. The patient experiences a cardiac arrest, and attempts to revive him or her fail. At autopsy, the pulmonary trunk was completely blocked by a sizable bilateral pulmonary embolism. He has experienced ongoing back discomfort for the previous few months, according to further information gleaned from the patient's wife. The photograph below depicts an autopsy of the vertebrae: Which of the following would the histologic analysis of the bone lesions in this patient most likely reveal?

A) Aggregates of pleomorphic neoplastic cells containing coarse, brown pigment
B) Cells with enlarged nuclei and prominent nucleoli forming irregular glands
C) Effacement of bone marrow with clusters of plasmablasts and plasma cells
D) Sheets of neoplastic cells with abundant clear cytoplasm
E) Tumor cells showing a complex papillary pattern and psammoma bodies

Correct Answer:

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