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A 61-Year-Old Lady Who Has Been Experiencing Eyesight Issues for the Past

Question 98

Multiple Choice

A 61-year-old lady who has been experiencing eyesight issues for the past six months visits the clinic. The patient claims that, particularly in the late afternoon and evening, her eyes quickly feel fatigued. She has smoked a pack of cigarettes every day for the past 35 years, but she doesn't drink or use illegal substances. The extraocular muscles are weak when examined physically. Sensation, deep tendon reflexes, and pupillary reflex are all normal. The exhibit displays a contrast-enhanced CT image of the chest.  A 61-year-old lady who has been experiencing eyesight issues for the past six months visits the clinic. The patient claims that, particularly in the late afternoon and evening, her eyes quickly feel fatigued. She has smoked a pack of cigarettes every day for the past 35 years, but she doesn't drink or use illegal substances. The extraocular muscles are weak when examined physically. Sensation, deep tendon reflexes, and pupillary reflex are all normal. The exhibit displays a contrast-enhanced CT image of the chest.    Which of the following is the most likely mechanism underlying this patient's symptoms? A) Antibodies against a neurotransmitter receptor B) Antibodies against a presynaptic calcium channel C) CD8<sup>+</sup> lymphocyte-mediated nerve fiber demyelination D) CD8<sup>+</sup> lymphocyte-mediated skeletal muscle damage E) Vascular deposition of circulating immune complexes Which of the following is the most likely mechanism underlying this patient's symptoms?


A) Antibodies against a neurotransmitter receptor
B) Antibodies against a presynaptic calcium channel
C) CD8+ lymphocyte-mediated nerve fiber demyelination
D) CD8+ lymphocyte-mediated skeletal muscle damage
E) Vascular deposition of circulating immune complexes

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