A 5-Year-Old Boy Is Brought by His Mother Because of a Diffculty

A 5-year-old boy is brought by his mother because of a diffculty walking. He has multiple respiratory infections. Cultured cells from this patient demonstrate a high rate of radiation-induced genetic mutation.  This patient is most likely to experience which of the following?

A) Neurofibrillary tangles in neocortex
B) Cerebellar atrophy
C) Loss of neurons in the substantia nigra
D) Atrophy of caudate nucleus
E) Posterior column degeneration
F) Presence of Lewy bodies

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