A 24-Year-Old Man Burns His Hand After Grasping the Handle

A 24-year-old man burns his hand after grasping the handle of a hot pan while preparing a meal.  Several minutes later, both the initial burn and the area around it are red without blistering.  When he presses on the burn, the tissue blanches.  Which of the following is most likely contributing to the reaction observed in this patient?

A) Gaps between endothelial cells in venules
B) Histamine release from mast cells
C) Neutrophil extravasation and degranulation
D) PDGF-mediated vascular proliferation
E) Prostaglandins produced by platelets

Correct Answer:

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