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A 13-Year-Old Boy with Growth Retardation, Microcephaly, Sun Sensitivity, and Recurring

Question 17

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A 13-year-old boy with growth retardation, microcephaly, sun sensitivity, and recurring infections is being examined for a hereditary genetic abnormality. The patient is the second kid born from a first cousin marriage. His parents and siblings are all OK, however two of his maternal relatives are experiencing identical indications and symptoms. The patient's genetic investigation indicates a deficiency in the BLM gene, which codes for DNA helicase. Which of the following is the enzyme's most likely place of action in the DNA replication fork depicted below? A 13-year-old boy with growth retardation, microcephaly, sun sensitivity, and recurring infections is being examined for a hereditary genetic abnormality. The patient is the second kid born from a first cousin marriage. His parents and siblings are all OK, however two of his maternal relatives are experiencing identical indications and symptoms. The patient's genetic investigation indicates a deficiency in the BLM gene, which codes for DNA helicase. Which of the following is the enzyme's most likely place of action in the DNA replication fork depicted below?   A) A B) B C) C D) D E) E F) F


A) A
B) B
C) C
D) D
E) E
F) F

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