A 13-Month-Old Boy Is Evaluated for Failure to Thrive and Delayed

A 13-month-old boy is evaluated for failure to thrive and delayed physical and mental development.  His mother reports that at 12 months he could barely lift his head and had difficulty sitting unsupported.  The toddler has not started babbling or forming words.  He is at the 10th percentile for height and 5th percentile for weight.  Laboratory results show Megaloblastic anemia and normal ammonia level. Urine specimens reveal increase orotic acid .  Supplementation with which of the following substances would most likely benefit this patient?

A) Ascorbic acid
B) Folic acid
C) Guanine
D) Iron
E) Pyridoxine
F) Uridine

Correct Answer:

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