Multiple Choice
A 55-year-old man comes to the office with a long history of fatigue and exertional dyspnea. He has early satiety and frequent upper abdominal discomfort. On physical examination, the patient has palpable splenomegaly but no lymphadenopathy. Laboratory tests are as follows: 
Reverse transcription polymerase chain reaction is used to diagnose chronic myelogenous leukemia in this patient. Which of the following is most likely to be detected by this test?
A) Chromosomal position of the BCR and ABL genes
B) DNA rearrangement in the BCR promoter region
C) Fusion protein containing BCR and ABL domains
D) Messenger RNA transcript containing BCR and ABL exons
E) Point mutation in the ABL enhancer region
Correct Answer:
Verified
Correct Answer:
Verified
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