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Hydroxyl Substituents in Alcohols Are Poor Leaving Groups, and Are

Question 91

Multiple Choice

Hydroxyl substituents in alcohols are poor leaving groups, and are not readily eliminated during substitution reactions.  Which of the following modifications would make the hydroxyl substituent of an alcohol a better leaving group?


A) Deprotonation
B) Addition of an acid
C) Addition of a strong base
D) Conversion to an acetal

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